Abstract: Based on the interdisciplinary concept, this study fully utilizes the existing achievements by multi-source heterogeneous data integrated processing methods, as well as multi-techniques of satellite-aero-ground-well-drilling-logging-testing to investigate the ground substrate of Taizhou City in the alluvial lacustrine plain characterized by dense river network. With the classification, spatial distribution, and physicochemical properties, the results have established a classification system for ground substrate types in Lixiahe-Yangtze River delta alluvial lacustrine plain, delineated the spatial distribution characteristics of ground substrate supporting the regional territorial space ecosystem, and clarified the physicochemical properties of ground substrate in farmland, wetland, woodland, and urban-rural construction land in the study area, which can provide data support services for the overall planning of regional territorial space and ecological environmental protection and restoration.